Drivers of MERS-CoV Emergence in Qatar
Identifieur interne : 000E30 ( Main/Exploration ); précédent : 000E29; suivant : 000E31Drivers of MERS-CoV Emergence in Qatar
Auteurs : Elmoubasher Farag ; Reina S. Sikkema ; Tinka Vinks ; Md Mazharul Islam ; Mohamed Nour ; Hamad Al-Romaihi ; Mohammed Al Thani ; Muzzamil Atta ; Farhoud H. Alhajri ; Salih Al-Marri ; Mohd Alhajri ; Chantal Reusken ; Marion KoopmansSource :
- Viruses [ 1999-4915 ] ; 2018.
Descripteurs français
- KwdFr :
- ARN viral, Animaux, Chameaux (virologie), Coronavirus du syndrome respiratoire du Moyen-Orient (génétique), Coronavirus du syndrome respiratoire du Moyen-Orient (isolement et purification), Fermes, Humains, Infections à coronavirus (médecine vétérinaire), Infections à coronavirus (transmission), Infections à coronavirus (épidémiologie), Mode de vie, Phylogénie, Qatar (épidémiologie), Réservoirs d'agents pathogènes (médecine vétérinaire), Réservoirs d'agents pathogènes (virologie), Zoonoses (transmission), Zoonoses (virologie), Zoonoses (épidémiologie), Élevage.
- MESH :
- génétique : Coronavirus du syndrome respiratoire du Moyen-Orient.
- isolement et purification : Coronavirus du syndrome respiratoire du Moyen-Orient.
- médecine vétérinaire : Infections à coronavirus, Réservoirs d'agents pathogènes.
- virologie : Chameaux, Réservoirs d'agents pathogènes, Zoonoses.
- épidémiologie : Infections à coronavirus, Qatar, Zoonoses.
- ARN viral, Animaux, Fermes, Humains, Mode de vie, Phylogénie, Élevage.
- Wicri :
- geographic : Qatar.
English descriptors
- KwdEn :
- Animal Husbandry, Animals, Camelus (virology), Coronavirus Infections (epidemiology), Coronavirus Infections (transmission), Coronavirus Infections (veterinary), Disease Reservoirs (veterinary), Disease Reservoirs (virology), Farms, Humans, Life Style, Middle East Respiratory Syndrome Coronavirus (genetics), Middle East Respiratory Syndrome Coronavirus (isolation & purification), Phylogeny, Qatar (epidemiology), RNA, Viral, Zoonoses (epidemiology), Zoonoses (transmission), Zoonoses (virology).
- MESH :
- chemical : RNA, Viral.
- geographic , epidemiology : Qatar.
- epidemiology : Coronavirus Infections, Zoonoses.
- genetics : Middle East Respiratory Syndrome Coronavirus.
- isolation & purification : Middle East Respiratory Syndrome Coronavirus.
- transmission : Coronavirus Infections, Zoonoses.
- veterinary : Coronavirus Infections, Disease Reservoirs.
- virology : Camelus, Disease Reservoirs, Zoonoses.
- Animal Husbandry, Animals, Farms, Humans, Life Style, Phylogeny.
Abstract
MERS-CoV (Middle East respiratory syndrome corona virus) antibodies were detected in camels since 1983, but the first human case was only detected in 2012. This study sought to identify and quantify possible drivers for the MERS-CoV emergence and spillover to humans. A list of potential human, animal and environmental drivers for disease emergence were identified from literature. Trends in possible drivers were analyzed from national and international databases, and through structured interviews with experts in Qatar. The discovery and exploitation of oil and gas led to a 5-fold increase in Qatar GDP coupled with a 7-fold population growth in the past 30 years. The lifestyle gradually transformed from Bedouin life to urban sedentary life, along with a sharp increase in obesity and other comorbidities. Owing to substantial governmental support, camel husbandry and competitions flourished, exacerbating the already rapidly occurring desertification that forced banning of free grazing in 2005. Consequently, camels were housed in compact barns alongside their workers. The transition in husbandry leading to high density camel farming along with increased exposure to humans, combined with the increase of camel movement for the racing and breeding industry, have led to a convergence of factors driving spillover of MERS-CoV from camels to humans.
Url:
DOI: 10.3390/v11010022
PubMed: 30602691
PubMed Central: 6356962
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Pmc, to step Corpus: 000B34
- to stream Pmc, to step Curation: 000B34
- to stream Pmc, to step Checkpoint: 000337
- to stream PubMed, to step Corpus: 000C55
- to stream PubMed, to step Curation: 000C55
- to stream PubMed, to step Checkpoint: 000C47
- to stream Ncbi, to step Merge: 000836
- to stream Ncbi, to step Curation: 000836
- to stream Ncbi, to step Checkpoint: 000836
- to stream Main, to step Merge: 000E32
- to stream Main, to step Curation: 000E30
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Drivers of MERS-CoV Emergence in Qatar</title><author><name sortKey="Farag, Elmoubasher" sort="Farag, Elmoubasher" uniqKey="Farag E" first="Elmoubasher" last="Farag">Elmoubasher Farag</name><affiliation><nlm:aff id="af1-viruses-11-00022">Ministry of Public of Health, Doha 42, Qatar;<email>mnour@moph.gov.qa</email> (M.N.);<email>halromaihi@moph.gov.qa</email> (H.A.-R.);<email>malthani@moph.gov.qa</email> (M.A.T.);<email>dralmarri@moph.gov.qa</email> (S.A.-M.);<email>malhajri1@moph.gov.qa</email> (M.A.)</nlm:aff></affiliation></author><author><name sortKey="Sikkema, Reina S" sort="Sikkema, Reina S" uniqKey="Sikkema R" first="Reina S." last="Sikkema">Reina S. Sikkema</name><affiliation><nlm:aff id="af2-viruses-11-00022">Department of Viroscience, Erasmus University Medical Center, Wytemaweg 80, 3015 CN Rotterdam, The Netherlands;<email>c.reusken@erasmusmc.nl</email> (C.R.);<email>m.koopmans@erasmusmc.nl</email> (M.K.)</nlm:aff></affiliation></author><author><name sortKey="Vinks, Tinka" sort="Vinks, Tinka" uniqKey="Vinks T" first="Tinka" last="Vinks">Tinka Vinks</name><affiliation><nlm:aff id="af3-viruses-11-00022">Division Veterinary Public Health, Institute of Risk Assessment Sciences, Faculty of Veterinary Medicine, Yalelaan 2, 3584 CM Utrecht, The Netherlands;<email>tinkavinks@gmail.com</email></nlm:aff></affiliation></author><author><name sortKey="Islam, Md Mazharul" sort="Islam, Md Mazharul" uniqKey="Islam M" first="Md Mazharul" last="Islam">Md Mazharul Islam</name><affiliation><nlm:aff id="af4-viruses-11-00022">Department of Animal Resources, Ministry of Municipality and Environment, Doha 35081, Qatar;<email>walidbdvet@gmail.com</email> (M.M.I.);<email>muzamilata@yahoo.com</email> (M.A.);<email>m6066@mme.gov.qa</email> (F.H.A.)</nlm:aff></affiliation></author><author><name sortKey="Nour, Mohamed" sort="Nour, Mohamed" uniqKey="Nour M" first="Mohamed" last="Nour">Mohamed Nour</name><affiliation><nlm:aff id="af1-viruses-11-00022">Ministry of Public of Health, Doha 42, Qatar;<email>mnour@moph.gov.qa</email> (M.N.);<email>halromaihi@moph.gov.qa</email> (H.A.-R.);<email>malthani@moph.gov.qa</email> (M.A.T.);<email>dralmarri@moph.gov.qa</email> (S.A.-M.);<email>malhajri1@moph.gov.qa</email> (M.A.)</nlm:aff></affiliation></author><author><name sortKey="Al Romaihi, Hamad" sort="Al Romaihi, Hamad" uniqKey="Al Romaihi H" first="Hamad" last="Al-Romaihi">Hamad Al-Romaihi</name><affiliation><nlm:aff id="af1-viruses-11-00022">Ministry of Public of Health, Doha 42, Qatar;<email>mnour@moph.gov.qa</email> (M.N.);<email>halromaihi@moph.gov.qa</email> (H.A.-R.);<email>malthani@moph.gov.qa</email> (M.A.T.);<email>dralmarri@moph.gov.qa</email> (S.A.-M.);<email>malhajri1@moph.gov.qa</email> (M.A.)</nlm:aff></affiliation></author><author><name sortKey="Al Thani, Mohammed" sort="Al Thani, Mohammed" uniqKey="Al Thani M" first="Mohammed" last="Al Thani">Mohammed Al Thani</name><affiliation><nlm:aff id="af1-viruses-11-00022">Ministry of Public of Health, Doha 42, Qatar;<email>mnour@moph.gov.qa</email> (M.N.);<email>halromaihi@moph.gov.qa</email> (H.A.-R.);<email>malthani@moph.gov.qa</email> (M.A.T.);<email>dralmarri@moph.gov.qa</email> (S.A.-M.);<email>malhajri1@moph.gov.qa</email> (M.A.)</nlm:aff></affiliation></author><author><name sortKey="Atta, Muzzamil" sort="Atta, Muzzamil" uniqKey="Atta M" first="Muzzamil" last="Atta">Muzzamil Atta</name><affiliation><nlm:aff id="af4-viruses-11-00022">Department of Animal Resources, Ministry of Municipality and Environment, Doha 35081, Qatar;<email>walidbdvet@gmail.com</email> (M.M.I.);<email>muzamilata@yahoo.com</email> (M.A.);<email>m6066@mme.gov.qa</email> (F.H.A.)</nlm:aff></affiliation></author><author><name sortKey="Alhajri, Farhoud H" sort="Alhajri, Farhoud H" uniqKey="Alhajri F" first="Farhoud H." last="Alhajri">Farhoud H. Alhajri</name><affiliation><nlm:aff id="af4-viruses-11-00022">Department of Animal Resources, Ministry of Municipality and Environment, Doha 35081, Qatar;<email>walidbdvet@gmail.com</email> (M.M.I.);<email>muzamilata@yahoo.com</email> (M.A.);<email>m6066@mme.gov.qa</email> (F.H.A.)</nlm:aff></affiliation></author><author><name sortKey="Al Marri, Salih" sort="Al Marri, Salih" uniqKey="Al Marri S" first="Salih" last="Al-Marri">Salih Al-Marri</name><affiliation><nlm:aff id="af1-viruses-11-00022">Ministry of Public of Health, Doha 42, Qatar;<email>mnour@moph.gov.qa</email> (M.N.);<email>halromaihi@moph.gov.qa</email> (H.A.-R.);<email>malthani@moph.gov.qa</email> (M.A.T.);<email>dralmarri@moph.gov.qa</email> (S.A.-M.);<email>malhajri1@moph.gov.qa</email> (M.A.)</nlm:aff></affiliation></author><author><name sortKey="Alhajri, Mohd" sort="Alhajri, Mohd" uniqKey="Alhajri M" first="Mohd" last="Alhajri">Mohd Alhajri</name><affiliation><nlm:aff id="af1-viruses-11-00022">Ministry of Public of Health, Doha 42, Qatar;<email>mnour@moph.gov.qa</email> (M.N.);<email>halromaihi@moph.gov.qa</email> (H.A.-R.);<email>malthani@moph.gov.qa</email> (M.A.T.);<email>dralmarri@moph.gov.qa</email> (S.A.-M.);<email>malhajri1@moph.gov.qa</email> (M.A.)</nlm:aff></affiliation></author><author><name sortKey="Reusken, Chantal" sort="Reusken, Chantal" uniqKey="Reusken C" first="Chantal" last="Reusken">Chantal Reusken</name><affiliation><nlm:aff id="af2-viruses-11-00022">Department of Viroscience, Erasmus University Medical Center, Wytemaweg 80, 3015 CN Rotterdam, The Netherlands;<email>c.reusken@erasmusmc.nl</email> (C.R.);<email>m.koopmans@erasmusmc.nl</email> (M.K.)</nlm:aff></affiliation></author><author><name sortKey="Koopmans, Marion" sort="Koopmans, Marion" uniqKey="Koopmans M" first="Marion" last="Koopmans">Marion Koopmans</name><affiliation><nlm:aff id="af2-viruses-11-00022">Department of Viroscience, Erasmus University Medical Center, Wytemaweg 80, 3015 CN Rotterdam, The Netherlands;<email>c.reusken@erasmusmc.nl</email> (C.R.);<email>m.koopmans@erasmusmc.nl</email> (M.K.)</nlm:aff></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">30602691</idno><idno type="pmc">6356962</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356962</idno><idno type="RBID">PMC:6356962</idno><idno type="doi">10.3390/v11010022</idno><date when="2018">2018</date><idno type="wicri:Area/Pmc/Corpus">000B34</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000B34</idno><idno type="wicri:Area/Pmc/Curation">000B34</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000B34</idno><idno type="wicri:Area/Pmc/Checkpoint">000337</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000337</idno><idno type="wicri:source">PubMed</idno><idno type="RBID">pubmed:30602691</idno><idno type="wicri:Area/PubMed/Corpus">000C55</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000C55</idno><idno type="wicri:Area/PubMed/Curation">000C55</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000C55</idno><idno type="wicri:Area/PubMed/Checkpoint">000C47</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000C47</idno><idno type="wicri:Area/Ncbi/Merge">000836</idno><idno type="wicri:Area/Ncbi/Curation">000836</idno><idno type="wicri:Area/Ncbi/Checkpoint">000836</idno><idno type="wicri:Area/Main/Merge">000E32</idno><idno type="wicri:Area/Main/Curation">000E30</idno><idno type="wicri:Area/Main/Exploration">000E30</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Drivers of MERS-CoV Emergence in Qatar</title><author><name sortKey="Farag, Elmoubasher" sort="Farag, Elmoubasher" uniqKey="Farag E" first="Elmoubasher" last="Farag">Elmoubasher Farag</name><affiliation><nlm:aff id="af1-viruses-11-00022">Ministry of Public of Health, Doha 42, Qatar;<email>mnour@moph.gov.qa</email> (M.N.);<email>halromaihi@moph.gov.qa</email> (H.A.-R.);<email>malthani@moph.gov.qa</email> (M.A.T.);<email>dralmarri@moph.gov.qa</email> (S.A.-M.);<email>malhajri1@moph.gov.qa</email> (M.A.)</nlm:aff></affiliation></author><author><name sortKey="Sikkema, Reina S" sort="Sikkema, Reina S" uniqKey="Sikkema R" first="Reina S." last="Sikkema">Reina S. Sikkema</name><affiliation><nlm:aff id="af2-viruses-11-00022">Department of Viroscience, Erasmus University Medical Center, Wytemaweg 80, 3015 CN Rotterdam, The Netherlands;<email>c.reusken@erasmusmc.nl</email> (C.R.);<email>m.koopmans@erasmusmc.nl</email> (M.K.)</nlm:aff></affiliation></author><author><name sortKey="Vinks, Tinka" sort="Vinks, Tinka" uniqKey="Vinks T" first="Tinka" last="Vinks">Tinka Vinks</name><affiliation><nlm:aff id="af3-viruses-11-00022">Division Veterinary Public Health, Institute of Risk Assessment Sciences, Faculty of Veterinary Medicine, Yalelaan 2, 3584 CM Utrecht, The Netherlands;<email>tinkavinks@gmail.com</email></nlm:aff></affiliation></author><author><name sortKey="Islam, Md Mazharul" sort="Islam, Md Mazharul" uniqKey="Islam M" first="Md Mazharul" last="Islam">Md Mazharul Islam</name><affiliation><nlm:aff id="af4-viruses-11-00022">Department of Animal Resources, Ministry of Municipality and Environment, Doha 35081, Qatar;<email>walidbdvet@gmail.com</email> (M.M.I.);<email>muzamilata@yahoo.com</email> (M.A.);<email>m6066@mme.gov.qa</email> (F.H.A.)</nlm:aff></affiliation></author><author><name sortKey="Nour, Mohamed" sort="Nour, Mohamed" uniqKey="Nour M" first="Mohamed" last="Nour">Mohamed Nour</name><affiliation><nlm:aff id="af1-viruses-11-00022">Ministry of Public of Health, Doha 42, Qatar;<email>mnour@moph.gov.qa</email> (M.N.);<email>halromaihi@moph.gov.qa</email> (H.A.-R.);<email>malthani@moph.gov.qa</email> (M.A.T.);<email>dralmarri@moph.gov.qa</email> (S.A.-M.);<email>malhajri1@moph.gov.qa</email> (M.A.)</nlm:aff></affiliation></author><author><name sortKey="Al Romaihi, Hamad" sort="Al Romaihi, Hamad" uniqKey="Al Romaihi H" first="Hamad" last="Al-Romaihi">Hamad Al-Romaihi</name><affiliation><nlm:aff id="af1-viruses-11-00022">Ministry of Public of Health, Doha 42, Qatar;<email>mnour@moph.gov.qa</email> (M.N.);<email>halromaihi@moph.gov.qa</email> (H.A.-R.);<email>malthani@moph.gov.qa</email> (M.A.T.);<email>dralmarri@moph.gov.qa</email> (S.A.-M.);<email>malhajri1@moph.gov.qa</email> (M.A.)</nlm:aff></affiliation></author><author><name sortKey="Al Thani, Mohammed" sort="Al Thani, Mohammed" uniqKey="Al Thani M" first="Mohammed" last="Al Thani">Mohammed Al Thani</name><affiliation><nlm:aff id="af1-viruses-11-00022">Ministry of Public of Health, Doha 42, Qatar;<email>mnour@moph.gov.qa</email> (M.N.);<email>halromaihi@moph.gov.qa</email> (H.A.-R.);<email>malthani@moph.gov.qa</email> (M.A.T.);<email>dralmarri@moph.gov.qa</email> (S.A.-M.);<email>malhajri1@moph.gov.qa</email> (M.A.)</nlm:aff></affiliation></author><author><name sortKey="Atta, Muzzamil" sort="Atta, Muzzamil" uniqKey="Atta M" first="Muzzamil" last="Atta">Muzzamil Atta</name><affiliation><nlm:aff id="af4-viruses-11-00022">Department of Animal Resources, Ministry of Municipality and Environment, Doha 35081, Qatar;<email>walidbdvet@gmail.com</email> (M.M.I.);<email>muzamilata@yahoo.com</email> (M.A.);<email>m6066@mme.gov.qa</email> (F.H.A.)</nlm:aff></affiliation></author><author><name sortKey="Alhajri, Farhoud H" sort="Alhajri, Farhoud H" uniqKey="Alhajri F" first="Farhoud H." last="Alhajri">Farhoud H. Alhajri</name><affiliation><nlm:aff id="af4-viruses-11-00022">Department of Animal Resources, Ministry of Municipality and Environment, Doha 35081, Qatar;<email>walidbdvet@gmail.com</email> (M.M.I.);<email>muzamilata@yahoo.com</email> (M.A.);<email>m6066@mme.gov.qa</email> (F.H.A.)</nlm:aff></affiliation></author><author><name sortKey="Al Marri, Salih" sort="Al Marri, Salih" uniqKey="Al Marri S" first="Salih" last="Al-Marri">Salih Al-Marri</name><affiliation><nlm:aff id="af1-viruses-11-00022">Ministry of Public of Health, Doha 42, Qatar;<email>mnour@moph.gov.qa</email> (M.N.);<email>halromaihi@moph.gov.qa</email> (H.A.-R.);<email>malthani@moph.gov.qa</email> (M.A.T.);<email>dralmarri@moph.gov.qa</email> (S.A.-M.);<email>malhajri1@moph.gov.qa</email> (M.A.)</nlm:aff></affiliation></author><author><name sortKey="Alhajri, Mohd" sort="Alhajri, Mohd" uniqKey="Alhajri M" first="Mohd" last="Alhajri">Mohd Alhajri</name><affiliation><nlm:aff id="af1-viruses-11-00022">Ministry of Public of Health, Doha 42, Qatar;<email>mnour@moph.gov.qa</email> (M.N.);<email>halromaihi@moph.gov.qa</email> (H.A.-R.);<email>malthani@moph.gov.qa</email> (M.A.T.);<email>dralmarri@moph.gov.qa</email> (S.A.-M.);<email>malhajri1@moph.gov.qa</email> (M.A.)</nlm:aff></affiliation></author><author><name sortKey="Reusken, Chantal" sort="Reusken, Chantal" uniqKey="Reusken C" first="Chantal" last="Reusken">Chantal Reusken</name><affiliation><nlm:aff id="af2-viruses-11-00022">Department of Viroscience, Erasmus University Medical Center, Wytemaweg 80, 3015 CN Rotterdam, The Netherlands;<email>c.reusken@erasmusmc.nl</email> (C.R.);<email>m.koopmans@erasmusmc.nl</email> (M.K.)</nlm:aff></affiliation></author><author><name sortKey="Koopmans, Marion" sort="Koopmans, Marion" uniqKey="Koopmans M" first="Marion" last="Koopmans">Marion Koopmans</name><affiliation><nlm:aff id="af2-viruses-11-00022">Department of Viroscience, Erasmus University Medical Center, Wytemaweg 80, 3015 CN Rotterdam, The Netherlands;<email>c.reusken@erasmusmc.nl</email> (C.R.);<email>m.koopmans@erasmusmc.nl</email> (M.K.)</nlm:aff></affiliation></author></analytic><series><title level="j">Viruses</title><idno type="eISSN">1999-4915</idno><imprint><date when="2018">2018</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Animal Husbandry</term><term>Animals</term><term>Camelus (virology)</term><term>Coronavirus Infections (epidemiology)</term><term>Coronavirus Infections (transmission)</term><term>Coronavirus Infections (veterinary)</term><term>Disease Reservoirs (veterinary)</term><term>Disease Reservoirs (virology)</term><term>Farms</term><term>Humans</term><term>Life Style</term><term>Middle East Respiratory Syndrome Coronavirus (genetics)</term><term>Middle East Respiratory Syndrome Coronavirus (isolation & purification)</term><term>Phylogeny</term><term>Qatar (epidemiology)</term><term>RNA, Viral</term><term>Zoonoses (epidemiology)</term><term>Zoonoses (transmission)</term><term>Zoonoses (virology)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>ARN viral</term><term>Animaux</term><term>Chameaux (virologie)</term><term>Coronavirus du syndrome respiratoire du Moyen-Orient (génétique)</term><term>Coronavirus du syndrome respiratoire du Moyen-Orient (isolement et purification)</term><term>Fermes</term><term>Humains</term><term>Infections à coronavirus (médecine vétérinaire)</term><term>Infections à coronavirus (transmission)</term><term>Infections à coronavirus (épidémiologie)</term><term>Mode de vie</term><term>Phylogénie</term><term>Qatar (épidémiologie)</term><term>Réservoirs d'agents pathogènes (médecine vétérinaire)</term><term>Réservoirs d'agents pathogènes (virologie)</term><term>Zoonoses (transmission)</term><term>Zoonoses (virologie)</term><term>Zoonoses (épidémiologie)</term><term>Élevage</term></keywords><keywords scheme="MESH" type="chemical" xml:lang="en"><term>RNA, Viral</term></keywords><keywords scheme="MESH" type="geographic" qualifier="epidemiology" xml:lang="en"><term>Qatar</term></keywords><keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Coronavirus Infections</term><term>Zoonoses</term></keywords><keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Middle East Respiratory Syndrome Coronavirus</term></keywords><keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>Coronavirus du syndrome respiratoire du Moyen-Orient</term></keywords><keywords scheme="MESH" qualifier="isolation & purification" xml:lang="en"><term>Middle East Respiratory Syndrome Coronavirus</term></keywords><keywords scheme="MESH" qualifier="isolement et purification" xml:lang="fr"><term>Coronavirus du syndrome respiratoire du Moyen-Orient</term></keywords><keywords scheme="MESH" qualifier="médecine vétérinaire" xml:lang="fr"><term>Infections à coronavirus</term><term>Réservoirs d'agents pathogènes</term></keywords><keywords scheme="MESH" qualifier="transmission" xml:lang="en"><term>Coronavirus Infections</term><term>Zoonoses</term></keywords><keywords scheme="MESH" qualifier="veterinary" xml:lang="en"><term>Coronavirus Infections</term><term>Disease Reservoirs</term></keywords><keywords scheme="MESH" qualifier="virologie" xml:lang="fr"><term>Chameaux</term><term>Réservoirs d'agents pathogènes</term><term>Zoonoses</term></keywords><keywords scheme="MESH" qualifier="virology" xml:lang="en"><term>Camelus</term><term>Disease Reservoirs</term><term>Zoonoses</term></keywords><keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Infections à coronavirus</term><term>Qatar</term><term>Zoonoses</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Animal Husbandry</term><term>Animals</term><term>Farms</term><term>Humans</term><term>Life Style</term><term>Phylogeny</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>ARN viral</term><term>Animaux</term><term>Fermes</term><term>Humains</term><term>Mode de vie</term><term>Phylogénie</term><term>Élevage</term></keywords><keywords scheme="Wicri" type="geographic" xml:lang="fr"><term>Qatar</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>MERS-CoV (Middle East respiratory syndrome corona virus) antibodies were detected in camels since 1983, but the first human case was only detected in 2012. This study sought to identify and quantify possible drivers for the MERS-CoV emergence and spillover to humans. A list of potential human, animal and environmental drivers for disease emergence were identified from literature. Trends in possible drivers were analyzed from national and international databases, and through structured interviews with experts in Qatar. The discovery and exploitation of oil and gas led to a 5-fold increase in Qatar GDP coupled with a 7-fold population growth in the past 30 years. The lifestyle gradually transformed from Bedouin life to urban sedentary life, along with a sharp increase in obesity and other comorbidities. Owing to substantial governmental support, camel husbandry and competitions flourished, exacerbating the already rapidly occurring desertification that forced banning of free grazing in 2005. Consequently, camels were housed in compact barns alongside their workers. The transition in husbandry leading to high density camel farming along with increased exposure to humans, combined with the increase of camel movement for the racing and breeding industry, have led to a convergence of factors driving spillover of MERS-CoV from camels to humans.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Jones, K E" uniqKey="Jones K">K.E. Jones</name></author><author><name sortKey="Patel, N G" uniqKey="Patel N">N.G. Patel</name></author><author><name sortKey="Levy, M A" uniqKey="Levy M">M.A. Levy</name></author><author><name sortKey="Storeygard, A" uniqKey="Storeygard A">A. Storeygard</name></author><author><name sortKey="Balk, D" uniqKey="Balk D">D. Balk</name></author><author><name sortKey="Gittleman, J L" uniqKey="Gittleman J">J.L. Gittleman</name></author><author><name sortKey="Daszak, P" uniqKey="Daszak P">P. Daszak</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Coltart, C E M" uniqKey="Coltart C">C.E.M. Coltart</name></author><author><name sortKey="Lindsey, B" uniqKey="Lindsey B">B. Lindsey</name></author><author><name sortKey="Ghinai, I" uniqKey="Ghinai I">I. Ghinai</name></author><author><name sortKey="Johnson, A M" uniqKey="Johnson A">A.M. Johnson</name></author><author><name sortKey="Heymann, D L" uniqKey="Heymann D">D.L. Heymann</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zumla, A" uniqKey="Zumla A">A. Zumla</name></author><author><name sortKey="Hui, D S" uniqKey="Hui D">D.S. Hui</name></author><author><name sortKey="Perlman, S" uniqKey="Perlman S">S. Perlman</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Reusken, C B" uniqKey="Reusken C">C.B. Reusken</name></author><author><name sortKey="Raj, V S" uniqKey="Raj V">V.S. Raj</name></author><author><name sortKey="Koopmans, M P" uniqKey="Koopmans M">M.P. Koopmans</name></author><author><name sortKey="Haagmans, B L" uniqKey="Haagmans B">B.L. Haagmans</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Azhar, E I" uniqKey="Azhar E">E.I. Azhar</name></author><author><name sortKey="El Kafrawy, S A" uniqKey="El Kafrawy S">S.A. El-Kafrawy</name></author><author><name sortKey="Farraj, S A" uniqKey="Farraj S">S.A. Farraj</name></author><author><name sortKey="Hassan, A M" uniqKey="Hassan A">A.M. Hassan</name></author><author><name sortKey="Al Saeed, M S" uniqKey="Al Saeed M">M.S. Al-Saeed</name></author><author><name sortKey="Hashem, A M" uniqKey="Hashem A">A.M. Hashem</name></author><author><name sortKey="Madani, T A" uniqKey="Madani T">T.A. Madani</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Arwady, M A" uniqKey="Arwady M">M.A. Arwady</name></author><author><name sortKey="Alraddadi, B" uniqKey="Alraddadi B">B. Alraddadi</name></author><author><name sortKey="Basler, C" uniqKey="Basler C">C. Basler</name></author><author><name sortKey="Azhar, E I" uniqKey="Azhar E">E.I. Azhar</name></author><author><name sortKey="Abuelzein, E" uniqKey="Abuelzein E">E. Abuelzein</name></author><author><name sortKey="Sindy, A I" uniqKey="Sindy A">A.I. Sindy</name></author><author><name sortKey="Sadiq, B M B" uniqKey="Sadiq B">B.M.B. Sadiq</name></author><author><name sortKey="Althaqafi, A O" uniqKey="Althaqafi A">A.O. Althaqafi</name></author><author><name sortKey="Shabouni, O" uniqKey="Shabouni O">O. Shabouni</name></author><author><name sortKey="Banjar, A" uniqKey="Banjar A">A. Banjar</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Cho, S Y" uniqKey="Cho S">S.Y. Cho</name></author><author><name sortKey="Kang, J" uniqKey="Kang J">J. Kang</name></author><author><name sortKey="Ha, Y E" uniqKey="Ha Y">Y.E. Ha</name></author><author><name sortKey="Park, G E" uniqKey="Park G">G.E. Park</name></author><author><name sortKey="Lee, J Y" uniqKey="Lee J">J.Y. Lee</name></author><author><name sortKey="Ko, J" uniqKey="Ko J">J. Ko</name></author><author><name sortKey="Lee, J Y" uniqKey="Lee J">J.Y. Lee</name></author><author><name sortKey="Kim, J M" uniqKey="Kim J">J.M. Kim</name></author><author><name sortKey="Kang, C" uniqKey="Kang C">C. Kang</name></author><author><name sortKey="Jo, I J" uniqKey="Jo I">I.J. Jo</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Alagaili, A N" uniqKey="Alagaili A">A.N. Alagaili</name></author><author><name sortKey="Briese, T" uniqKey="Briese T">T. Briese</name></author><author><name sortKey="Mishra, N" uniqKey="Mishra N">N. Mishra</name></author><author><name sortKey="Kapoor, V" uniqKey="Kapoor V">V. Kapoor</name></author><author><name sortKey="Sameroff, S C" uniqKey="Sameroff S">S.C. Sameroff</name></author><author><name sortKey="Wit, E" uniqKey="Wit E">E. Wit</name></author><author><name sortKey="Munster, V J" uniqKey="Munster V">V.J. Munster</name></author><author><name sortKey="Hensley, L E" uniqKey="Hensley L">L.E. Hensley</name></author><author><name sortKey="Zalmout, I S" uniqKey="Zalmout I">I.S. Zalmout</name></author><author><name sortKey="Kapoor, A" uniqKey="Kapoor A">A. Kapoor</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lee, J Y" uniqKey="Lee J">J.Y. Lee</name></author><author><name sortKey="Kim, Y" uniqKey="Kim Y">Y. Kim</name></author><author><name sortKey="Chung, E H" uniqKey="Chung E">E.H. Chung</name></author><author><name sortKey="Kim, D" uniqKey="Kim D">D. Kim</name></author><author><name sortKey="Jeong, I" uniqKey="Jeong I">I. Jeong</name></author><author><name sortKey="Lee, J Y" uniqKey="Lee J">J.Y. Lee</name></author><author><name sortKey="Kim, Y" uniqKey="Kim Y">Y. Kim</name></author><author><name sortKey="Chung, E H" uniqKey="Chung E">E.H. Chung</name></author><author><name sortKey="Kim, D" uniqKey="Kim D">D. Kim</name></author><author><name sortKey="Jeong, I" uniqKey="Jeong I">I. Jeong</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Muller, M A" uniqKey="Muller M">M.A. Müller</name></author><author><name sortKey="Corman, V M" uniqKey="Corman V">V.M. Corman</name></author><author><name sortKey="Jores, J" uniqKey="Jores J">J. Jores</name></author><author><name sortKey="Meyer, B" uniqKey="Meyer B">B. Meyer</name></author><author><name sortKey="Younan, M" uniqKey="Younan M">M. Younan</name></author><author><name sortKey="Liljander, A" uniqKey="Liljander A">A. Liljander</name></author><author><name sortKey="Bosch, B" uniqKey="Bosch B">B. Bosch</name></author><author><name sortKey="Lattwein, E" uniqKey="Lattwein E">E. Lattwein</name></author><author><name sortKey="Hilali, M" uniqKey="Hilali M">M. Hilali</name></author><author><name sortKey="Musa, B E" uniqKey="Musa B">B.E. Musa</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hassell, J M" uniqKey="Hassell J">J.M. Hassell</name></author><author><name sortKey="Begon, M" uniqKey="Begon M">M. Begon</name></author><author><name sortKey="Ward, M J" uniqKey="Ward M">M.J. Ward</name></author><author><name sortKey="Fevre, E M" uniqKey="Fevre E">E.M. Fèvre</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Jones, B A" uniqKey="Jones B">B.A. Jones</name></author><author><name sortKey="Grace, D" uniqKey="Grace D">D. Grace</name></author><author><name sortKey="Kock, R" uniqKey="Kock R">R. Kock</name></author><author><name sortKey="Alonso, S" uniqKey="Alonso S">S. Alonso</name></author><author><name sortKey="Rushton, J" uniqKey="Rushton J">J. Rushton</name></author><author><name sortKey="Said, M Y" uniqKey="Said M">M.Y. Said</name></author><author><name sortKey="Kckeever, D" uniqKey="Kckeever D">D. KcKeever</name></author><author><name sortKey="Mutua, F" uniqKey="Mutua F">F. Mutua</name></author><author><name sortKey="Young, J" uniqKey="Young J">J. Young</name></author><author><name sortKey="Mcdermott, J" uniqKey="Mcdermott J">J. McDermott</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hui, E K" uniqKey="Hui E">E.K. Hui</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hemida, M G" uniqKey="Hemida M">M.G. Hemida</name></author><author><name sortKey="Elmoslemany, A" uniqKey="Elmoslemany A">A. Elmoslemany</name></author><author><name sortKey="Al Hizab, F" uniqKey="Al Hizab F">F. Al-Hizab</name></author><author><name sortKey="Alnaeem, A" uniqKey="Alnaeem A">A. Alnaeem</name></author><author><name sortKey="Almathen, F" uniqKey="Almathen F">F. Almathen</name></author><author><name sortKey="Faye, B" uniqKey="Faye B">B. Faye</name></author><author><name sortKey="Chu, D K W" uniqKey="Chu D">D.K.W. Chu</name></author><author><name sortKey="Perera, R A P M" uniqKey="Perera R">R.A.P.M. Perera</name></author><author><name sortKey="Peiris, M" uniqKey="Peiris M">M. Peiris</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Cauchemez, S" uniqKey="Cauchemez S">S. Cauchemez</name></author><author><name sortKey="Nouvellet, P" uniqKey="Nouvellet P">P. Nouvellet</name></author><author><name sortKey="Cori, A" uniqKey="Cori A">A. Cori</name></author><author><name sortKey="Jombart, T" uniqKey="Jombart T">T. Jombart</name></author><author><name sortKey="Garske, T" uniqKey="Garske T">T. Garske</name></author><author><name sortKey="Clapham, H" uniqKey="Clapham H">H. Clapham</name></author><author><name sortKey="Moore, S" uniqKey="Moore S">S. Moore</name></author><author><name sortKey="Mills, H L" uniqKey="Mills H">H.L. Mills</name></author><author><name sortKey="Salje, H" uniqKey="Salje H">H. Salje</name></author><author><name sortKey="Collins, C" uniqKey="Collins C">C. Collins</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hobbs, M" uniqKey="Hobbs M">M. Hobbs</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Al Janahi, B M" uniqKey="Al Janahi B">B.M. Al Janahi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Crystal, J" uniqKey="Crystal J">J. Crystal</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Dougherty, R L" uniqKey="Dougherty R">R.L. Dougherty</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Snoj, J" uniqKey="Snoj J">J. Snoj</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Bakri, A H" uniqKey="Bakri A">A.H. Bakri</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Elford, C J" uniqKey="Elford C">C.J. Elford</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zaki, A M" uniqKey="Zaki A">A.M. Zaki</name></author><author><name sortKey="Boheemen, S V" uniqKey="Boheemen S">S.V. Boheemen</name></author><author><name sortKey="Bestebroer, T M" uniqKey="Bestebroer T">T.M. Bestebroer</name></author><author><name sortKey="Osterhaus, A D" uniqKey="Osterhaus A">A.D. Osterhaus</name></author><author><name sortKey="Fouchier, R A" uniqKey="Fouchier R">R.A. Fouchier</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Khalfallah, A I" uniqKey="Khalfallah A">A.I. Khalfallah</name></author><author><name sortKey="Lu, X" uniqKey="Lu X">X. Lu</name></author><author><name sortKey="Mubarak, A I A" uniqKey="Mubarak A">A.I.A. Mubarak</name></author><author><name sortKey="Dalab, A H S" uniqKey="Dalab A">A.H.S. Dalab</name></author><author><name sortKey="Al Busadah, K A S" uniqKey="Al Busadah K">K.A.S. Al-Busadah</name></author><author><name sortKey="Erdman, D D" uniqKey="Erdman D">D.D. Erdman</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Badawi, A" uniqKey="Badawi A">A. Badawi</name></author><author><name sortKey="Ryo, S G" uniqKey="Ryo S">S.G. Ryo</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lu, G" uniqKey="Lu G">G. Lu</name></author><author><name sortKey="Wang, Q" uniqKey="Wang Q">Q. Wang</name></author><author><name sortKey="Gao, G F" uniqKey="Gao G">G.F. Gao</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Letko, M" uniqKey="Letko M">M. Letko</name></author><author><name sortKey="Miazgowicz, K" uniqKey="Miazgowicz K">K. Miazgowicz</name></author><author><name sortKey="Mcminn, R" uniqKey="Mcminn R">R. McMinn</name></author><author><name sortKey="Seifert, S N" uniqKey="Seifert S">S.N. Seifert</name></author><author><name sortKey="Sola, I" uniqKey="Sola I">I. Sola</name></author><author><name sortKey="Enjuanes, L" uniqKey="Enjuanes L">L. Enjuanes</name></author><author><name sortKey="Carmody, A" uniqKey="Carmody A">A. Carmody</name></author><author><name sortKey="Van Doremalen, N" uniqKey="Van Doremalen N">N. van Doremalen</name></author><author><name sortKey="Munster, V" uniqKey="Munster V">V. Munster</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Adney, D R" uniqKey="Adney D">D.R. Adney</name></author><author><name sortKey="Doremalen, N V" uniqKey="Doremalen N">N.V. Doremalen</name></author><author><name sortKey="Brown, V R" uniqKey="Brown V">V.R. Brown</name></author><author><name sortKey="Bushmaker, T" uniqKey="Bushmaker T">T. Bushmaker</name></author><author><name sortKey="Scott, D" uniqKey="Scott D">D. Scott</name></author><author><name sortKey="Wit, E D" uniqKey="Wit E">E.D. Wit</name></author><author><name sortKey="Bowen, R A" uniqKey="Bowen R">R.A. Bowen</name></author><author><name sortKey="Munster, V J" uniqKey="Munster V">V.J. Munster</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chu, D K W" uniqKey="Chu D">D.K.W. Chu</name></author><author><name sortKey="Hui, K P Y" uniqKey="Hui K">K.P.Y. Hui</name></author><author><name sortKey="Perera, R A P M" uniqKey="Perera R">R.A.P.M. Perera</name></author><author><name sortKey="Miguel, E" uniqKey="Miguel E">E. Miguel</name></author><author><name sortKey="Niemeyer, D" uniqKey="Niemeyer D">D. Niemeyer</name></author><author><name sortKey="Zhao, J" uniqKey="Zhao J">J. Zhao</name></author><author><name sortKey="Channappanavar, R" uniqKey="Channappanavar R">R. Channappanavar</name></author><author><name sortKey="Dudas, G" uniqKey="Dudas G">G. Dudas</name></author><author><name sortKey="Oladipo, J O" uniqKey="Oladipo J">J.O. Oladipo</name></author><author><name sortKey="Traore, A" uniqKey="Traore A">A. Traoré</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list></list><tree><noCountry><name sortKey="Al Marri, Salih" sort="Al Marri, Salih" uniqKey="Al Marri S" first="Salih" last="Al-Marri">Salih Al-Marri</name><name sortKey="Al Romaihi, Hamad" sort="Al Romaihi, Hamad" uniqKey="Al Romaihi H" first="Hamad" last="Al-Romaihi">Hamad Al-Romaihi</name><name sortKey="Al Thani, Mohammed" sort="Al Thani, Mohammed" uniqKey="Al Thani M" first="Mohammed" last="Al Thani">Mohammed Al Thani</name><name sortKey="Alhajri, Farhoud H" sort="Alhajri, Farhoud H" uniqKey="Alhajri F" first="Farhoud H." last="Alhajri">Farhoud H. Alhajri</name><name sortKey="Alhajri, Mohd" sort="Alhajri, Mohd" uniqKey="Alhajri M" first="Mohd" last="Alhajri">Mohd Alhajri</name><name sortKey="Atta, Muzzamil" sort="Atta, Muzzamil" uniqKey="Atta M" first="Muzzamil" last="Atta">Muzzamil Atta</name><name sortKey="Farag, Elmoubasher" sort="Farag, Elmoubasher" uniqKey="Farag E" first="Elmoubasher" last="Farag">Elmoubasher Farag</name><name sortKey="Islam, Md Mazharul" sort="Islam, Md Mazharul" uniqKey="Islam M" first="Md Mazharul" last="Islam">Md Mazharul Islam</name><name sortKey="Koopmans, Marion" sort="Koopmans, Marion" uniqKey="Koopmans M" first="Marion" last="Koopmans">Marion Koopmans</name><name sortKey="Nour, Mohamed" sort="Nour, Mohamed" uniqKey="Nour M" first="Mohamed" last="Nour">Mohamed Nour</name><name sortKey="Reusken, Chantal" sort="Reusken, Chantal" uniqKey="Reusken C" first="Chantal" last="Reusken">Chantal Reusken</name><name sortKey="Sikkema, Reina S" sort="Sikkema, Reina S" uniqKey="Sikkema R" first="Reina S." last="Sikkema">Reina S. Sikkema</name><name sortKey="Vinks, Tinka" sort="Vinks, Tinka" uniqKey="Vinks T" first="Tinka" last="Vinks">Tinka Vinks</name></noCountry></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/CovidV2/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000E30 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000E30 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Sante
|area= CovidV2
|flux= Main
|étape= Exploration
|type= RBID
|clé= PMC:6356962
|texte= Drivers of MERS-CoV Emergence in Qatar
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:30602691" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \
| NlmPubMed2Wicri -a CovidV2
| This area was generated with Dilib version V0.6.33. |  |